| #P001 | chemical | health | mandatory | 1,2-Dichloroethane | drinking water | MAC | 0.005 mg/L | Consequently, a MAC of 0.005 mg/L (5 µg/L) for 1,2-DCA is established | Based on an estimated lifetime excess risk of cancers of 10-6 | high |
| #P002 | chemical | health | mandatory | 1,2-Dichloroethane | drinking water | MAC | 5 µg/L | Consequently, a MAC of 0.005 mg/L (5 µg/L) for 1,2-DCA is established | Based on an estimated lifetime excess risk of cancers of 10-6 | high |
| #P003 | design | treatment | mandatory | 1,2-DCA (NSF/ANSI Standard 53) | drinking water | requirement | 0.005 mg/L | For a drinking water treatment device to be certified to NSF/ANSI Standards 53 for the reduction of 1,2-DCA alone, the device must be capable of reduction an average influent concentration of 0.015 mg/L to a maximum of 0.005 mg/L. | Certification to NSF/ANSI Standard 53 for reduction of 1,2-DCA alone | high |
| #P004 | design | treatment | mandatory | 1,2-DCA (NSF/ANSI Standard 53 surrogate testing) | drinking water | requirement | 0.0048 mg/L | For a drinking water treatment device to be certified to NSF/ANSI Standards 53 by surrogate testing, the device must be capable of reduction of an influent concentration of 0.088 mg/L 1,2-DCA to a maximum product water concentration of 0.0048 mg/L | Certification to NSF/ANSI Standard 53 by surrogate testing | high |
| #P005 | design | treatment | mandatory | 1,2-DCA (NSF/ANSI Standard 58 surrogate testing) | drinking water | requirement | 0.0048 mg/L | For a drinking water treatment device to be certified to NSF/ANSI Standards 58 by surrogate testing, the device must be capable of a 95% reduction of 1,2-DCA, from an influent concentration of 0.088 mg/L to a maximum of 0.0048 mg/L | Certification to NSF/ANSI Standard 58 by surrogate testing (reverse osmosis) | high |
| #P006 | chemical | health | guidance | 1,2-Dichloroethane (Non-cancer HBV) | drinking water | treatment_goal | 0.26 mg/L | The HBV for 1,2-DCA in drinking water for non-cancer effects is derived as follows: HBV = [0.078 mg/kg bw/day × 70 kg × 0.20] / 4.2 L-eq/day = 0.26 mg/L (260 µg/L) | Based on renal tubular regeneration in female F344 rats | high |
| #P007 | chemical | health | guidance | 1,2-Dichloroethane (Cancer HBV - 10-5 risk) | drinking water | treatment_goal | 0.05 mg/L | Table 4: HBV based on the three different estimated risk levels. 10-5 risk level: 0.05 mg/L | Based on lifetime excess risk of 10-5 | high |
| #P008 | chemical | health | guidance | 1,2-Dichloroethane (Cancer HBV - 10-4 risk) | drinking water | treatment_goal | 0.5 mg/L | Table 4: HBV based on the three different estimated risk levels. 10-4 risk level: 0.5 mg/L | Based on lifetime excess risk of 10-4 | high |
| #P009 | design | treatment | guideline | BAT 1,2-DCA Removal Efficiency | drinking water | treatment_goal | 99 % | The U.S. EPA has identified packed tower aeration (PTA) and granular activated carbon (GAC) as the best available technologies (BATs) for 1,2-DCA removal in drinking water and the agency considers a 99% reduction to be achievable under all anticipated conditions | Using PTA or GAC technologies | high |
| #P010 | operational | reporting | mandatory | 1,2-Dichloroethane Practical Quantitation Level (PQL) | drinking water | requirement | 5 µg/L | The current U.S. EPA practical quantitation level (PQL) for 1,2-DCA is 5 µg/L. | | high |
| #P011 | operational | reporting | guidance | Minimum Quantitation Level (Method SM 6200B) | drinking water | requirement | 0.22 µg/L | The minimum quantitation levels, defined as the lowest level that can be quantified accurately, are 0.22 µg/L and 0.296 µg/L for methods SM 6200B and SM 6200C respectively. | Defined as the lowest level that can be quantified accurately | high |
| #P012 | operational | reporting | guidance | Minimum Quantitation Level (Method SM 6200C) | drinking water | requirement | 0.296 µg/L | The minimum quantitation levels, defined as the lowest level that can be quantified accurately, are 0.22 µg/L and 0.296 µg/L for methods SM 6200B and SM 6200C respectively. | Defined as the lowest level that can be quantified accurately | high |
| #P013 | operational | reporting | guidance | Estimated Quantitation Level (EQL) | drinking water | requirement | 0.5 µg/L | EPA retained 0.5 µg/L as an estimated quantitation level (EQL) for 1,2-DCA which is an estimate of the possible lower bound for a PQL and take into consideration laboratory analytical limits nationwide | Estimate of the possible lower bound for a Practical Quantitation Level (PQL) | high |
| #P014 | design | treatment | mandatory | NSF/ANSI Standard 58 Reduction Efficiency | drinking water | requirement | 95 % | For a drinking water treatment device to be certified to NSF/ANSI Standards 58 by surrogate testing, the device must be capable of a 95% reduction of 1,2-DCA, from an influent concentration of 0.088 mg/L to a maximum of 0.0048 mg/L | Certification to NSF/ANSI Standard 58 by surrogate testing | high |
| #P015 | operational | health | mandatory | Exposure Significance Threshold | drinking water | requirement | 10 % | Both the dermal and inhalation routes of exposure for a VOC are considered significant if they contribute at least 10% of the drinking water consumption level | Applicable to VOC exposure assessment | high |
| #P016 | operational | health | mandatory | Standard Canadian Drinking Water Consumption Rate | drinking water | requirement | 1.5 L/day | standard Canadian drinking water consumption rate of 1.5 L/day | Used in multi-route exposure assessment | high |
| #P017 | operational | health | mandatory | Total Litre-equivalent Daily Exposure (1,2-DCA) | drinking water | requirement | 4.2 L-eq/day | total litre-equivalent daily exposure to 1,2-DCA in drinking water was estimated to be 4.2 L-eq (rounded) | Accounting for multiroute exposure using PBPK model | high |
| #P018 | operational | reporting | mandatory | Method Detection Limit (MDL) - Method 502.2 | drinking water | requirement | 0.03 µg/L | Method 502.2 revision 2.1... has a method detection limit (MDL) of 0.03 µg/L. | Using electrolytic conductivity detector (ELCD) and photoionization detector (PID) in series | high |
| #P019 | operational | reporting | mandatory | Method Detection Limit (MDL) - Method 524.3 | drinking water | requirement | 0.025 µg/L | Method 524.3 is an updated version of method 524.2 and has a detection limit of 0.025 µg/L. | Optimization of purge-and-trap parameters | high |
| #P020 | operational | reporting | mandatory | Method Detection Limit (MDL) - Method 524.2 | drinking water | requirement | 0.02 - 0.06 µg/L | Depending on the GC column and GC/MS interface used, the method has an MDL range of 0.02 - 0.06 µg/L (U.S. EPA, 1995, 2009a). | Interfaced to a mass spectrometer (MS) | high |
| #P021 | operational | reporting | guidance | Method Detection Limit (MDL) - SM 6200B | drinking water | requirement | 0.055 µg/L | Method SM 6200B has a MDL of 0.055 µg/L | | high |
| #P022 | operational | reporting | guidance | Method Detection Limit (MDL) - SM 6200C | drinking water | requirement | 0.074 µg/L | SM 6200C has a MDL of 0.074 µg/L. | | high |
| #P023 | chemical | health | guidance | Tolerable Daily Intake (TDI) | drinking water | treatment_goal | 0.078 mg/kg bw/day | TDI = [78 mg/kg bw/day] / 1000 = 0.078 mg/kg bw/day | Based on BMDL10 for renal tubular regeneration and uncertainty factor of 1000 | high |
| #P024 | operational | health | guidance | Significance Threshold - Skin Permeability Coefficient (Kp) | drinking water | requirement | > 0.024 cm/h | For a tier 1 goal of 0.15 L-eq, the skin permeability coefficient (Kp) for 1,2-DCA should be higher than 0.024 cm/h (Krishnan and Carrier, 2008). | To determine if dermal route of exposure contributes a minimum of 10% of consumption level | high |
| #P025 | operational | health | guidance | Significance Threshold - Air:Water Concentration Factor (Fair:water) | drinking water | requirement | > 0.00063 ratio | for a tier 1 goal of 0.15 L-eq, the average ratio of air to water 1,2-DCA concentration factor (Fair:water) should be greater than 0.00063 | To determine if inhalation route contributes at least 10% of consumption level | high |
| #P026 | operational | health | guidance | Dermal Exposure (L-eq) - PBPK Approach | drinking water | requirement | 2.06 L-eq | the litre-equivalent contributions for dermal and inhalation exposure were determined to be 2.06 and 0.68 L-eq, respectively. | Calculated using human PBPK model for a 30-minute bathing scenario | high |
| #P027 | operational | health | guidance | Inhalation Exposure (L-eq) - PBPK Approach | drinking water | requirement | 0.68 L-eq | the litre-equivalent contributions for dermal and inhalation exposure were determined to be 2.06 and 0.68 L-eq, respectively. | Calculated using human PBPK model for a 30-minute bathing scenario | high |
| #P028 | chemical | health | guidance | 1,2-Dichloroethane (Non-cancer HBV - µg/L) | drinking water | treatment_goal | 260 µg/L | The HBV for 1,2-DCA in drinking water for non-cancer effects is derived as follows: HBV = 0.26 mg/L (260 µg/L) | Based on renal tubular regeneration | high |
| #P029 | operational | reporting | guidance | Potential Practical Quantitation Level (PQL) Range | drinking water | requirement | 0.3 - 0.6 µg/L | The agency determined that the assessment data supported the reduction of the PQL and estimated a lower possible PQL in the range of 0.3 to 0.6 µg/L. | Supported by U.S. EPA assessment of performance evaluation data | high |
| #P030 | operational | health | guidance | Total Daily Exposure (Conservative Approach) | drinking water | requirement | 4.6 L-eq/day | Assuming one showering or bathing event per day and adding these values to the standard Canadian drinking water consumption rate of 1.5 L/day, this results in a total daily exposure of 4.6 L-eq (rounded from 4.56 L-eq). | Using two-tier approach (1.63 L-eq dermal and 1.43 L-eq inhalation) | high |
| #P031 | chemical | health | guidance | 1,2-Dichloroethane (Cancer HBV - 10-6 risk) | drinking water | treatment_goal | 0.005 mg/L | Table 4: HBV based on the three different estimated risk levels. 10-6 risk level: 0.005 mg/L | Based on lifetime excess risk of 10-6 | high |
| #P032 | operational | health | guidance | Dermal Exposure (L-eq) - Two-tier Approach | drinking water | requirement | 1.63 L-eq | Using the two-tier approach, the litre-equivalent were calculated as 1.63 L-eq for the dermal route | Calculated based on skin permeability coefficient of 0.259 cm/h | high |
| #P033 | operational | health | guidance | Inhalation Exposure (L-eq) - Two-tier Approach | drinking water | requirement | 1.43 L-eq | Using the two-tier approach, the litre-equivalent were calculated as... 1.43 L-eq for the inhalation route. | Based on calculated air:water concentration factor of 0.00604 | high |
| #P034 | design | treatment | mandatory | NSF/ANSI Standard 53 Influent Challenge Concentration | drinking water | requirement | 0.015 mg/L | the device must be capable of reduction an average influent concentration of 0.015 mg/L to a maximum of 0.005 mg/L. | Certification to NSF/ANSI Standard 53 for 1,2-DCA alone | high |
| #P035 | design | treatment | mandatory | NSF/ANSI Standard 53/58 Surrogate Influent Challenge Concentration | drinking water | requirement | 0.088 mg/L | the device must be capable of reduction of an influent concentration of 0.088 mg/L 1,2-DCA to a maximum product water concentration of 0.0048 mg/L | Certification by surrogate testing | high |
| #P036 | operational | health | guidance | Standard Adult Exposed Skin Area | drinking water | requirement | 18000 cm2 | A is the area of skin exposed, assumed to be 18 000 cm2 for adults | Used in multi-route dermal exposure calculations | high |
| #P037 | operational | health | guidance | Adult Alveolar Ventilation Rate | drinking water | requirement | 675 L/h | Qalv is the adult alveolar ventilation rate, assumed to be 675 L/h | Used in multi-route inhalation exposure calculations | high |
| #P038 | operational | health | guidance | Standard Adult Body Weight | drinking water | requirement | 70 kg | 70 kg is the average body weight of an adult | Used in health-based value (HBV) derivations | high |
| #P039 | operational | health | mandatory | Allocation Factor (Drinking Water) | drinking water | requirement | 0.20 dimensionless | floor allocation factor (20%) of the daily intake allocated to drinking water | Used in the calculation of the MAC and HBV | high |
| #P040 | operational | health | mandatory | Uncertainty Factor (TDI Derivation) | drinking water | requirement | 1000 dimensionless | 1000 is the uncertainty factor | Applied to BMDL10 for renal tubular regeneration | high |
| #P041 | chemical | health | guidance | Point of Departure (BMDL10) | drinking water | requirement | 78 mg/kg bw/day | 78 mg/kg bw/day is the BMDL10 for renal tubular regeneration in female F344 rats | Point of departure for non-cancer risk assessment | high |
| #P042 | chemical | health | guidance | Human External Dose (10-6 Risk Level) | drinking water | treatment_goal | 0.0003 mg/kg bw/day | Table 3: Humans (PBPK approach) 10-6 risk level: 0.0003 mg/kg bw/day | Cancer external human dose based on PBPK approach | high |
| #P043 | chemical | health | guidance | Human External Dose (10-5 Risk Level) | drinking water | treatment_goal | 0.003 mg/kg bw/day | Table 3: Humans (PBPK approach) 10-5 risk level: 0.003 mg/kg bw/day | Cancer external human dose based on PBPK approach | high |
| #P044 | chemical | health | guidance | Human External Dose (10-4 Risk Level) | drinking water | treatment_goal | 0.03 mg/kg bw/day | Table 3: Humans (PBPK approach) 10-4 risk level: 0.03 mg/kg bw/day | Cancer external human dose based on PBPK approach | high |